CELLEC BIOTEK AG devel­ops and com­mer­cial­izes per­fu­sion-based biore­ac­tor sys­tems for 3D cell cul­ture. The result­ing tis­sues are used as advanced mod­els of devel­op­ment, phys­i­ol­o­gy, pathol­o­gy, and drug test­ing, and prospec­tive­ly as engi­neered grafts for tis­sue and organ regeneration.

InSphero sets the stan­dard for in vit­ro test­ing of nov­el drugs in the phar­ma­ceu­ti­cal indus­try. Found­ed in 2009, InSphero’s patent-pend­ing tech­nolo­gies and meth­ods enable large-scale, repro­ducible pro­duc­tion of scaf­fold-free 3D micro­tis­sues for appli­ca­tion in the field of liv­er safe­ty, meta­bol­ic dis­ease, and immune oncol­o­gy. In recent years, inno­v­a­tive organ-on-chip con­cepts for automa­tion-com­pat­i­ble mul­ti-organ exper­i­ments have been pre­sent­ed, ele­vat­ing in vit­ro test­ing to a next lev­el of phys­i­o­log­i­cal relevance.

Job­st Tech­nolo­gies is the glob­al com­pe­tence and per­for­mance leader for biosen­sor mon­i­tor­ing appli­ca­tions. The microflu­idic oper­a­tion of the mul­ti-para­met­ric sen­sor sys­tems allows for real-time mon­i­tor­ing and con­trol of meta­bol­ic para­me­ters (Lac­tate, Glu­cose, Glu­t­a­mine) crit­i­cal for organ on a chip systems.

Microflu­idic Chip­Shop is one of the lead­ing microflu­idic prod­ucts and ser­vice providers. A unique fea­ture of the com­pa­ny is its cat­a­logue with a huge vari­ety of off-the-shelf microflu­idic com­po­nents and sys­tems, allow­ing a low-cost rapid access to lab-on-a-chip tech­nolo­gies, such as Organ-on-Chip.

React4life is an Ital­ian biotech com­pa­ny which patent­ed MIVO® (Mul­ti In Vit­ro Organ).
This cut­ting-edge micro­phys­i­o­log­i­cal sys­tem enables researchers to over­come the lim­its of cur­rent in vit­ro assays and ani­mal mod­els. It improves the reli­a­bil­i­ty and pre­dic­tiv­i­ty of sev­er­al appli­ca­tions: phar­ma­ceu­ti­cal drug-test­ing, per­son­al­ized med­i­cine, nov­el immuno-oncol­o­gy ther­a­pies, cos­met­ics, der­ma­tol­ogy, and nutraceutical.